Our nervous system is like an electrical wired system which passes messages or signals through nerve cells or neurons. The smooth functioning of the nervous system can be affected by many diseases and Parkinson’s disease is one of them. It is a progressive nervous system disorder that affects movement. The initial symptoms of the disease start off with small tremors in just one hand followed by gradual stiffness and slowing down of the movement. All the other symptoms can vary from person to person. They begin on one side of the body and remain worse in that side, even though the symptoms begin to affect both the sides.
- Posture and balance become impaired– The posture of an individual suffering from Parkinson’s disease can become stooped and can also have problems with maintaining body balance.
- Tremor accompanied by slow movement- the shaking often begins in one hand or finger. One may experience pill-rolling tremor where the patient rubs the thumb and the forefinger back and forth. Hands tremor even when at rest. Bradykinesia or slow movement makes it difficult to perform even the simplest of tasks. e.g. dragging of feet while walking.
- Loss of automatic movements due to rigid muscles- evens the performance of involuntary movements like smiling, blinking etc can be decreased. The stiffness in the muscles can be very painful and limit the range of movement.
- Speech and writing changes- Speech may become softer, slurred or hesitant before talking. Speech is usually in monotones Handwriting becomes smaller.
As the symptoms get worse, affected individuals can have other problems like depression, sleep problems, chewing and swallowing.
Parkinson’s disease usually starts around the age of 60 but at times it can start earlier too and men are more prone to it as compared to women.
What could be the causes of this condition? Neurons are special cells of the brain and unlike other cells of the body; neurons once destroyed cannot be replaced. In Parkinson’s disease, the neurons breakdown and die. Due to the loss of neurons, there is a decrease in the levels of a chemical messenger in the brain called dopamine which in turn leads to abnormal brain activities.
There are many factors that play a role in the development of this disease:
- Environmental factors- A small risk of Parkinson’s disease is due to the toxic chemicals like herbicides and pesticides that a person is exposed to.
- Genes- There are certain genetic mutations or changes in the gene that can result in this condition.
Many studies over the years have shown that there are many changes that occur in the brain of individuals suffering from Parkinson’s disease.
- Lewy bodies- Clumps of certain substances in the brain cells called Lewy bodies appear that can hold a clue to the real cause of Parkinson’s disease.
- Alpha-synuclein is a protein which is found within all Lewy bodies in a clumped up form that cannot be broken down.
An individual suffering from Parkinson’s disease can experience many other complications like:
- Blood pressure changes- He might feel dizzy while standing due to the sudden drop in blood pressure.
- Pain- The patient might experience pain in some parts of the body or throughout the body.
- Bladder problems- Inability to control urine or difficulty in urinating can also be experienced by the patient.
- Sexual dysfunction- There can be a decrease in sexual desire or performance.
- Depression- Along with depression, the patient might experience other emotions like fear, anxiety, and demotivation.
Nuramin by Bagdara Farms is a product that helps prevent and provide relief from the symptoms of Parkinson’s disease. This miraculous product owes its qualities to the presence of curcumin and turmerone that have many therapeutic properties.
- Curcumin is known to increase the levels of dopamine and acetylcholine which are necessary for the proper functioning of the brain.
- Oxidative stress is the main reason for many ailments in the body. Curcumin and turmerone are both known to reduce the extent of oxidative stress taking place in the body.
- The main cause of Parkinson’s disease is the death of neurons as a result of mitochondrial dysfunction. The ability of the curcumin to prevent neuronal cell death goes a long way in preventing the onset as well as the progression of the disease.
- As mentioned above, the protein alpha-synuclein leads to the formation of Lewy bodies in the brains of Parkinson’s patients. Curcumin inhibits the accumulation of alpha-synuclein.